منابع مشابه
Fluorine in medicinal chemistry.
Since its first use in the steroid field in the late 1950s, the use of fluorine in medicinal chemistry has become commonplace, with the small electronegative fluorine atom being a key part of the medicinal chemist's repertoire of substitutions used to modulate all aspects of molecular properties including potency, physical chemistry and pharmacokinetics. This review will highlight the special n...
متن کاملMolecular Medicinal Chemistry IDECEFYN
Several lymphoma T cell lines differ in membrane superficial markers and do not respond to the same drugs and compounds. Tilia x viridis (Bayer) Simonk nothosubspecie moltkei (Dippel) Xifreda is a plant widely distributed in Argentina. The aim of this work was to study comparatively the effects of dichloromethane extract and isolated compounds on BW 5147 and on another T lymphoma cell line EL-4...
متن کامل“ Medicinal Organometallic Chemistry ”
229 © 2011 Johnson Matthey http://dx.doi.org/10.1595/147106711X592899 http://www.platinummetalsreview.com/ Edited by Gérard Jaouen (Ecole Nationale Superieure de Chimie de Paris, France) and Nils Metzler-Nolte (Ruhr-Universität Bochum, Germany), Topics in Organometallic Chemistry, Vol. 32, Springer, Berlin, Heidelberg, Germany, 2010, 291 pages, ISBN: 978-3-642-13184-4, £171.00, €189.95, US$259....
متن کاملExpanding medicinal chemistry space.
Clinically useful drugs target a relatively small number of proteins that lie within a clearly defined and chemically accessible space. However, many high value biological targets lie outside this chemical space, and an ability to access such 'intractable' targets not amenable to traditional small molecule intervention would expand treatment options and be a major boost for patients and the pha...
متن کاملMedicinal chemistry section.
The Medicinal Chemistry Section is part of the Experimental Therapeutics Interdisciplinary Programme that is dedicated to early Drug Discovery activities in the oncology field. Our mission is to discover and to develop new anticancer agents based on novel hypotheses and targets generated by CNIO’s Basic Research Groups, and to do so in close collaboration with these groups. Medicinal chemists a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Chemical Education
سال: 1961
ISSN: 0021-9584,1938-1328
DOI: 10.1021/ed038p276.1